pentobarbital will reduce the level or influence of fostemsavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
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pentobarbital will reduce the level or impact of fosaprepitant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
pentobarbital will lower the extent or influence of gefitinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will reduce the extent or effect of conjugated estrogens by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
pentobarbital will minimize the extent or effect of pitolisant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Carefully. Pitolisant publicity is lowered by fifty% if coadministered with solid CYP3A4 inducers.
Observe Closely (two)pentobarbital will decrease the extent or influence of buprenorphine, extended-acting injection by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Intently. Sufferers who transfer to buprenorphine long-performing injection from transmucosal buprenorphine coadministered with CYP3A4 inducers must be monitored to make sure buprenorphine plasma degrees are suitable.
pentobarbital raises effects of ifosfamide by influencing hepatic enzyme CYP2B6 metabolism. Use Caution/Check. Coadministration of ifosfamide with CYP2B6 inducers may perhaps boost metabolism of ifosfamide to its metabolite. Watch for elevated effects/toxicities if coupled with CYP2B6 inducers.
pentobarbital will lessen the extent or influence of lorlatinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
Observe Closely (two)pentobarbital will reduce the extent or effect of oliceridine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of. If coadministration that has a CYP3A4 inducer is necessary, consider escalating oliceridine dose right until stable drug effects are reached; monitor for signs of opioid withdrawal.
pentobarbital will minimize the level or impact of imatinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Not known.
pentobarbital will lessen the extent or outcome of tacrolimus by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
pentobarbital will minimize the extent or result of eucalyptus by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Unfamiliar.
pentobarbital will reduce the level or effect of ramelteon by affecting hepatic/intestinal here enzyme CYP3A4 metabolism. Minor/Importance Not known.